This antibody detects recombinant human RIAM/APBB1IP in direct ELISAs.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
RIAM appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
Protein Aliases: amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein; Amyloid beta A4 precursor protein-binding family B member 1-interacting protein; APBB1-interacting protein 1; PREL-1; proline rich EVH1 ligand 1; Proline-rich EVH1 ligand 1; Proline-rich protein 48; Proline-rich protein 73; Rap1-GTP-interacting adapter molecule; Rap1-GTP-interacting adaptor molecule; Rap1-interacting adaptor molecule; RARP-1; Retinoic acid-responsive proline-rich protein 1; RIAM; RIAMRARP-1
Gene Aliases: 9930118P07Rik; APBB1IP; INAG1; PREL1; Prp48; RARP1; RIAM
Molecular Function: scaffold/adaptor protein