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Search Thermo Fisher Scientific
Recommended positive controls: 293T, HepG2, Neuro2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2.
Predicted reactivity: Mouse (94%), Rat (94%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SUDD, also known as RIOK3 (RIO kinase 3), is a 519 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed in a variety of tissues, SUDD catayzes the ATP-dependent phosphorylation of target proteins, thereby influencing signaling events throughout the cell. SUDD is expressed as two isoforms due to alternative splicing events.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homolog of the Aspergillus nidulans sudD gene product; RIO kinase 3; Serine/threonine-protein kinase RIO3; sudD (suppressor of bimD6, Aspergillus nidulans) homolog; sudD homolog; sudD suppressor of Aspergillus nidulans bimD6 homolog; sudD suppressor of bimD6 homolog; sudD, suppressor of bimD6 homolog; testicular secretory protein Li 47
Gene Aliases: 1200013N13Rik; D18Ertd331e; E130306C24Rik; RIOK3; SUDD
UniProt ID: (Human) O14730, (Mouse) Q9DBU3
Entrez Gene ID: (Human) 8780, (Rat) 361293, (Mouse) 66878
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