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Bethyl Laboratories
RKIP Polyclonal Antibody
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FIGURE: 1 / 1
RKIP Antibody (A304-493A) in WB
Detection of human and mouse RKIP by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-RKIP antibody (Product # A304-493A) (lot A304-493A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A304-493A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 137 to 187 of Human Raf Kinase Inhibitory Protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
Target Information
PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis luminal protein 210; epididymis secretory protein Li 34; epididymis secretory protein Li 96; HCNPpp; hippocampal cholinergic neurostimulating peptide; KIAA0299; LDGF; MDGF; MOCA; Neuropolypeptide h3; PEBP-1; Phosphatidylethanolamine-binding protein 1; PPBP; prostatic binding protein; Prostatic-binding protein; Raf kinase inhibitor protein; Raf kinase inhibitory protein; Raf-1 inhibitor protein; Raf-1 kinase inhibitor protein; RKIP; unnamed protein product
Gene Aliases: HCNP; HCNPpp; HEL-210; HEL-S-34; HEL-S-96; PBP; Pbp1; Pbpr; PEBP; PEBP-1; PEBP1; RKIP
UniProt ID: (Human) P30086, (Mouse) P70296
Entrez Gene ID: (Human) 5037, (Mouse) 23980
nucleotide binding
RNA binding
serine-type endopeptidase inhibitor activity
protein binding
ATP binding
lipid binding
phosphatidylethanolamine binding
enzyme binding
protein kinase binding
peptidase inhibitor activity
receptor binding
kinase binding
poly(A) RNA binding
mitogen-activated protein kinase binding
protease inhibitor
negative regulation of MAPK cascade
MAPK cascade
regulation of neurotransmitter levels
negative regulation of protein phosphorylation
regulation of the force of heart contraction
negative regulation of peptidase activity
positive regulation of cAMP-mediated signaling
positive regulation of mitotic nuclear division
sperm capacitation
positive regulation of acetylcholine metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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