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Proteintech
RLIM Polyclonal Antibody
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Product Details
16121-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RLIM Fusion Protein Ag9077 (276-350 aa encoded by BC013357)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SGPELLSRG LFAASGTRNA SQGAGSSDTA ASGESTGSGQ RPPTIVLDLQ VRRVRPGEYR QRDSIASRTR SRSQTP (276-350 aa encoded by BC013357)
Target Information
RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CTD-2530H13.3; DKFZp686N06224; E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase RNF12; FLJ25923; FLJ41093; FLJ42887; FLJ45986; Hoxa1 regulated; LIM domain-interacting RING finger protein; MGC15161; R-LIM; Renal carcinoma antigen NY-REN-43; RING finger LIM domain-binding protein; RING finger protein 12; ring zinc finger LIM domain binding protein; ring zinc finger protein NY-REN-43antigen; RING-type E3 ubiquitin transferase RLIM; unnamed protein product
Gene Aliases: AL022832; AW743871; Ha1r; MRX61; NY-REN-43; RLIM; Rlim1; RNF12; TOKAS
UniProt ID: (Human) Q9NVW2, (Mouse) Q9WTV7
Entrez Gene ID: (Human) 51132, (Rat) 317241, (Mouse) 19820
transcription corepressor activity
ubiquitin-protein transferase activity
zinc ion binding
transferase activity
metal ion binding
ubiquitin protein ligase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
negative regulation of transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
protein ubiquitination
negative regulation of sequence-specific DNA binding transcription factor activity
random inactivation of X chromosome
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of dosage compensation by inactivation of X chromosome
negative regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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