The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis.
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Protein Aliases: C3HC4-like zinc finger protein; MGC8715; RING finger protein 141; Zinc finger protein 230; Zinc finger protein FDZF2
Gene Aliases: 2610110L04Rik; AA792898; AU022812; FDZF2; RNF141; ZFP26; ZFP36; ZNF230
UniProt ID: (Human) Q8WVD5, (Mouse) Q99MB7, (Human) Q9UIE0
Entrez Gene ID: (Human) 50862, (Mouse) 67150, (Human) 7773
Molecular Function:
KRAB box transcription factor
transcription factor
zinc finger transcription factor
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