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Proteintech
RNF6 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
20437-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RNF6 Fusion Protein Ag14209 (1-300 aa encoded by BC034688)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MNQSRSRSD GGSEETLPQD HNHHENERRW QQERLHREEA YYQFINELND EDYRLMRDHN LLGTPGEITS EELQQRLDGV KEQLASQPDL RDGTNYRDSE VPRESSHEDS LLEWLNTFRR TGNATRSGQN GNQTWRAVSR TNPNNGEFRF SLEIHVNHEN RGFEIHGEDY TDIPLSDSNR DHTANRQQRS TSPVARRTRS QTSVNFNGSS SNIPRTRLAS RGQNPAEGSF STLGRLRNGI GGAAGIPRAN ASRTNFSSHT NQSGGSELRQ REGQRFGAAH VWENGARSNV TVRNTNQRLE P (1-300 aa encoded by BC034688)
Target Information
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp686P0776; ring finger protein (C3H2C3 type) 6; ring finger protein (C3H2C3 type) 6 isoform RNF6_1; ring finger protein (C3H2C3 type) 6 isoform RNF6_2; RING-H2; RING-H2 protein RNF-6; RING-type E3 ubiquitin transferase RNF6; RLIM-like protein; testis development-related; unnamed protein product
Gene Aliases: 1200013I08Rik; 5730419H05Rik
UniProt ID: (Human) Q9Y252, (Mouse) Q9DBU5
Entrez Gene ID: (Human) 6049, (Mouse) 74132
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
protein ubiquitination
negative regulation of axon extension
protein K27-linked ubiquitination
positive regulation of transcription, DNA-templated
regulation of androgen receptor signaling pathway
protein K48-linked ubiquitination
protein K6-linked ubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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