Immunogen sequence: VVDNVFPNCI LLLKLPGLEK LLHHVTEEKG NPEIDNKKYY KYSKEKTLKW LEKKVNQTVA ALKTNNVNVS SRVQSTAFFS GDQASTDKEE DYIRYAH
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 73%.
RNASEH2B is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. RNASEH2B is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication.
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Protein Aliases: AGS2; Aicardi-Goutieres syndrome 2 protein; Deleted in lymphocytic leukemia 8; DLEU8; Ribonuclease H2 subunit B; ribonuclease H2, subunit B; Ribonuclease HI subunit B; RNase H2 subunit B
Gene Aliases: AGS2; DLEU8; RNASEH2B
UniProt ID: (Human) Q5TBB1
Entrez Gene ID: (Human) 79621