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Invitrogen
RPL22 Polyclonal Antibody
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FIGURE: 1 / 2
RPL22 Antibody (PA5-85680) in IHC (P)
RPL22 Polyclonal Antibody detects RPL22 protein at cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. RPL22 Polyclonal Antibody (Product # PA5-85680) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-85680
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length human RPL22 Recombinant protein.
Conjugate
Form
Liquid
Concentration
0.92 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (95%), Xenopus laevis (92%), Pig (99%), Chicken (96%), Rhesus Monkey (99%).
Positive Control: HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36. 3-p36. 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S ribosomal protein L22; EAP; EBER-associated protein; Epstein-Barr virus small RNA-associated protein; Epstein-Barr-encoded RNA-associated protein; heparin-binding protein 15; Heparin-binding protein HBp15; Large ribosomal subunit protein eL22
Gene Aliases: EAP; HBP15; HBP15/L22; L22; RPL22
UniProt ID: (Human) P35268, (Rat) P47198
Entrez Gene ID: (Human) 6146, (Rat) 81768
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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