Proteintech

RPL3 Polyclonal Antibody

RPL3 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 19

RPL3 Antibody (11005-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HepG2 cells using 11005-1-AP (RPL3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

RPL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RPL3 Antibody in Immunoprecipitation (IP)

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Product Details

11005-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RPL3 Fusion Protein Ag1436 (153-403 aa encoded by BC012786)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.19 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This is a rabbit polyclonal antibody raised against the C terminus of human RPL3.

Immunogen sequence: MKKYCQVIR VIAHTQMRLL PLRQKKAHLM EIQVNGGTVA EKLDWARERL EQQVPVNQVF GQDEMIDVIG VTKGKGYKGV TSRWHTKKLP RKTHRGLRKV ACIGAWHPAR VAFSVARAGQ KGYHHRTEIN KKIYKIGQGY LIKDGKLIKN NASTDYDLSD KSINPLGGFV HYGEVTNDFV MLKGCVVGTK KRVLTLRKSL LVQTKRRALE KIDLKFIDTT SKFGHGRFQT MEEKKAFMGP LKKDRIAKEE GA (153-403 aa encoded by BC012786)

Target Information

This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The Rab5 effector FERRY links early endosomes with mRNA localization.

Molecular cell

Schuhmacher JS,Tom Dieck S,Christoforidis S,Landerer C,Davila Gallesio J,Hersemann L,Seifert S,Schäfer R,Giner A,Toth-Petroczy A,Kalaidzidis Y,Bohnsack KE,Bohnsack MT,Schuman EM,Zerial M

Thu Jun 01 00:00:00 EDT 2023

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.

Nucleic acids research

Milenkovic I,Santos Vieira HG,Lucas MC,Ruiz-Orera J,Patone G,Kesteven S,Wu J,Feneley M,Espadas G,Sabidó E,Hübner N,van Heesch S,Völkers M,Novoa EM

Fri Jun 23 00:00:00 EDT 2023

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart.

Nucleic acids research

Milenkovic I,Santos Vieira HG,Lucas MC,Ruiz-Orera J,Patone G,Kesteven S,Wu J,Feneley M,Espadas G,Sabidó E,Hübner N,van Heesch S,Völkers M,Novoa EM

Fri Jun 23 00:00:00 EDT 2023

Ribosomal RNA regulates chromosome clustering during mitosis.

Cell discovery

Ma K,Luo M,Xie G,Wang X,Li Q,Gao L,Yu H,Yu X

Tue May 31 00:00:00 EDT 2022

METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance.

eLife

Matsuura-Suzuki E,Shimazu T,Takahashi M,Kotoshiba K,Suzuki T,Kashiwagi K,Sohtome Y,Akakabe M,Sodeoka M,Dohmae N,Ito T,Shinkai Y,Iwasaki S

Wed Jun 08 00:00:00 EDT 2022

Preventing translational inhibition from ribosomal protein insufficiency by a herpes simplex virus-encoded ribosome-associated protein.

Proceedings of the National Academy of Sciences of the United States of America

Vink EI,Andrews J,Duffy C,Mohr I

Tue Nov 09 00:00:00 EST 2021

DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.

Carcinogenesis

Zhang X,Han J,Feng L,Zhi L,Jiang D,Yu B,Zhang Z,Gao B,Zhang C,Li M,Zhao L,Wang G

Thu Feb 11 00:00:00 EST 2021

Knockdown of Muscle-Specific Ribosomal Protein L3-Like Enhances Muscle Function in Healthy and Dystrophic Mice.

Nucleic acid therapeutics

Kao BR,Malerba A,Lu-Nguyen NB,Harish P,McCarthy JJ,Dickson G,Popplewell LJ

Wed Dec 01 00:00:00 EST 2021

RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation.

Aging

Chen C,Liu C,Niu Z,Li M,Zhang Y,Gao R,Chen H,Wang Q,Zhang S,Zhou R,Gan L,Zhang Z,Zhu T,Yu H,Liu J

Tue Jul 21 00:00:00 EDT 2020

Bioinformatics

Protein Aliases: 60S ribosomal protein L3; HIV-1 TAR RNA-binding protein B; J1 protein; Large ribosomal subunit protein uL3; ribosomal protein L3 homolog; ribosomal protein L3, isoform a; TARBP-B

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Gene Aliases: ASC-1; F2; J1; L3; OK/SW-cl.32; RPL3; TARBP-B

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UniProt ID: (Human) P39023, (Mouse) P27659

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Entrez Gene ID: (Human) 6122, (Mouse) 27367

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Function(s)

RNA binding structural constituent of ribosome protein binding poly(A) RNA binding ribosomal protein

Process(es)

ribosomal large subunit assembly nuclear-transcribed mRNA catabolic process, nonsense-mediated decay rRNA processing translation translational initiation SRP-dependent cotranslational protein targeting to membrane viral transcription cellular response to interleukin-4

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RPL3 Polyclonal Antibody

RPL3 Antibody (11005-1-AP) in ICC/IF

Product Details

11005-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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