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Product Details
PA5-101819
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RRAGA(Accession Q7L523), corresponding to amino acid residues N269-R313.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2851251
Product Specific Information
Antibody detects endogenous levels of total RRAGA/B.
Target Information
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenovirus E3 14.7 kDa-interacting protein 1; adenovirus E3-14.7K interacting protein 1; FIP-1; GTP-binding protein ragB; Rag A; Rag B; ragB; Ras-related GTP binding A; Ras-related GTP binding B; Ras-related GTP-binding protein A; Ras-related GTP-binding protein B; Ras-related GTP-binding protein ragA; RRAGA; rraga {ECO:0000312|RGD:619804}; RRAGB; rragB {ECO:0000312|RGD:619805}
Gene Aliases: 1300010C19Rik; AI255374; bA465E19.1; FIP-1; FIP1; RAGA; RAGB; RRAGA; RRAGB
UniProt ID: (Human) Q7L523, (Human) Q5VZM2, (Rat) Q63487, (Rat) Q63486, (Mouse) Q80X95, (Mouse) Q6NTA4
Entrez Gene ID: (Human) 10670, (Human) 10325, (Rat) 117043, (Rat) 117044, (Mouse) 68441, (Mouse) 245670
apoptotic process
cell cycle arrest
cell death
negative regulation of autophagy
macroautophagy
modulation by virus of host morphology or physiology
positive regulation of TOR signaling
cellular response to amino acid starvation
cellular protein localization
positive regulation of cytolysis
cellular response to amino acid stimulus
positive regulation of TORC1 signaling
regulation of autophagy
regulation of TOR signaling
biological_process
metabolic process
cellular response to starvation
regulation of cytolysis
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