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RUVBL1 Antibody (PA5-144643) in IHC (P)
Immunohistochemistry of RUVBL1 in paraffin-embedded mouse skeletal muscle tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with RUVBL1 polyclonal antibody (Product # PA5-144643) with a dilution of 1:400 for 1 hour at room te... View More
Product Details
PA5-144643
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within Human TIP49A aa 121-320/456.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3094093
Product Specific Information
Positive control: Hela cell lysate, MCF-7 cell lysate, NIH/3T3 cell lysate, mouse liver tissue lysate, mouse skeletal muscle tissue lysate, rat skin tissue lysate, Rat skeletal muscle lysate, human liver tissue, human testis tissue, rat trachea tissue, human fallopian tube tissue, mouse skeletal muscle tissue.^M
^M
Predicted band size: 50 kDa^M
^M
Subcellular Location: Cytoplasm, Cytoskeleton, Membrane, Nucleus.
Target Information
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; DNA helicase p50; ECP-54; INO80 complex subunit H; NMP 238; Nuclear matrix protein 238; Pontin 52; RuvB (E coli homolog)-like 1; RuvB-like 1; RuvB-like AAA ATPase 1; RuvB-like protein 1; TAP54-alpha; TATA binding protein interacting protein 49 kDa; TIP49a; TIP60-a; TIP60-associated protein 54-alpha
Gene Aliases: 2510009G06Rik; ECP-54; ECP54; INO80H; NMP 238; NMP238; PONTIN; Pontin52; RUVBL1; RVB1; TIH1; TIP49; TIP49A
UniProt ID: (Human) Q9Y265, (Rat) P60123, (Mouse) P60122
Entrez Gene ID: (Human) 8607, (Rat) 65137, (Mouse) 56505
DNA repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
mitotic nuclear division
positive regulation of plasminogen activation
DNA duplex unwinding
regulation of growth
histone H4 acetylation
histone H2A acetylation
cell division
regulation of fibroblast apoptotic process
cellular response to DNA damage stimulus
cell cycle
chromatin modification
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
box C/D snoRNP assembly
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
spermatogenesis
CENP-A containing nucleosome assembly
cell-cell adhesion
beta-catenin-TCF complex assembly
positive regulation of telomerase RNA localization to Cajal body
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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