NeoBiotechnologies

RXRB Monoclonal Antibody (PCRP-RXRB-2B6)

View all (9) RXRB antibodies

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Protocols

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RXRB Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemistry/Immunofluorescence analysis of PFA-fixed K562 cells using RXRB Monoclonal Antibody (Product # 6257-MSM1-P1ABX) followed by goat anti-mouse IgG-CF488 (green). CF640A phalloidin (red)..

RXRB Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human lymph node using RXRB Monoclonal Antibody (Product # 6257-MSM1-P1ABX).

RXRB Antibody in Flow Cytometry (Flow) — Flow Cytometry analysis of PFA-fixed HeLa cells using RXRB Monoclonal Antibody (Product # 6257-MSM1-P1ABX) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).

RXRB Antibody in Peptide array (ARRAY) — Analysis of Protein Array containing more than 19,000 full-length human proteins RXRB Monoclonal Antibody (Product # 6257-MSM1-P1ABX). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

RXRB Antibody — SDS-PAGE Analyis Purified RXRB Monoclonal Antibody (Product # 6257-MSM1-P1ABX). Confirmation of Purity and Integrity of Antibody.

Product Details

6257-MSM1-P1ABX

Applications	Tested Dilution	Publications
Western Blot (WB)	1-2 µg/mL	-
Immunohistochemistry (Paraffin) (IHC (P))	1-2 µg/mL	-
Immunocytochemistry (ICC/IF)	1-2 µg/mL	-
Flow Cytometry (Flow)	1-2 µg/10^6 cells	-
Peptide Array (Array)	Assay-dependent	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Mouse / IgG2a
Class	Monoclonal
Type	Antibody
Clone	PCRP-RXRB-2B6
Immunogen	Recombinant full-length human RXRB protein View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Protein A
Storage buffer	PBS, pH 7.4
Contains	no preservative
Storage conditions	-20°C or -80°C if preferred

Product Specific Information

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

Target Information

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DADB-100D22.1; MGC1831; MHC class I promoter binding protein; Nuclear receptor subfamily 2 group B member 2; Retinoic acid receptor RXR-beta; retinoid X receptor; Retinoid X receptor beta; retinoid X receptor, beta; RXR Beta

Gene Aliases: DAUDI6; H-2RIIBP; NR2B2; RCoR-1; RXRB

UniProt ID: (Human) P28702

Entrez Gene ID: (Human) 6257

Molecular Function: C4 zinc finger nuclear receptor

Function(s)

transcription initiation from RNA polymerase II promoter regulation of myelination steroid hormone mediated signaling pathway positive regulation of transcription from RNA polymerase II promoter retinoic acid receptor signaling pathway positive regulation of receptor activity

Process(es)

RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity transcription coactivator activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding 9-cis retinoic acid receptor activity protein binding zinc ion binding thyroid hormone receptor coactivator activity vitamin D receptor binding retinoic acid receptor binding thyroid hormone receptor binding protein heterodimerization activity

RXRB Monoclonal Antibody (PCRP-RXRB-2B6)

Product Details

6257-MSM1-P1ABX

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Peptide Array (Array)

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

References (0)

Bioinformatics

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