Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has four known isoforms: 3A, 3B, 3C and 3D. These proteins are expressed in the highest concentration in the brain and endocrine tissues and are involved in regulated exocytosis of hormones and neurotransmitters. Specifically Rab3's are thought to play a role in presynaptic vesicle trafficking and priming.
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Protein Aliases: brain antigen RAB3B; glioblastoma overexpressed; GTP-binding protein Rab-3D; Rab3D upregulated with myeloid differentiation; RAS-associated protein RAB3A; Ras-related protein Rab-3A; Ras-related protein Rab-3B; Ras-related protein Rab-3C; Ras-related protein Rab-3D; Ras-related small GTP binding protein 3A; small GTP-binding protein Rab3C
Gene Aliases: 2610528C18Rik; 2700062I01Rik; 3110015B08Rik; 3110037E15Rik; AI850886; C130057E11Rik; D2-2; GOV; RAB16; RAB3; RAB3A; RAB3B; RAB3C; RAB3D; RAD3D