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Product Details
13874-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
S1PR5/EDG8 Fusion Protein Ag4928 (213-398 aa encoded by BC034703)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ARIYCQVRA NARRLPARPG TAGTTSTRAR RKPRSLALLR TLSVVLLAFV ACWGPLFLLL LLDVACPART CPVLLQADPF LGLAMANSLL NPIIYTLTNR DLRHALLRLV CCGRHSCGRD PSGSQQSASA AEASGGLRRC LPPGLDGSFS GSERSSPQRD GLDTSGSTGS PGAPTAARTL VSEPAAD (213-398 aa encoded by BC034703 )
Target Information
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; Lysophospholipid receptor B4; S1P receptor 5; S1P receptor Edg-8; S1P(5) receptor; Sphingosine 1-phosphate receptor 5; Sphingosine 1-phosphate receptor Edg-8; sphingosine 1-phosphate receptor EDG8; sphingosine-1-phosphate receptor LPB4
Gene Aliases: Edg-8; EDG8; Lpb4; S1P5; S1PR5; SPPR-1; SPPR-2
UniProt ID: (Human) Q9H228, (Mouse) Q91X56
Entrez Gene ID: (Human) 53637, (Mouse) 94226
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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