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S6PDH is an enzyme that belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as an acceptor. The systematic name of this enzyme class is D-sorbitol-6-phosphate: NAD+ 2-oxidoreductase. Other names in common use include ketosephosphate reductase, ketosephosphate reductase, D-sorbitol 6-phosphate dehydrogenase, D-sorbitol-6-phosphate dehydrogenase, sorbitol-6-P-dehydrogenase, and D-glucitol-6-phosphate dehydrogenase. This enzyme participates in fructose and mannose metabolism.
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