This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: ETQSVSSFSS GPTSPSEMPD QFPAVVRPGS LDLPSPVSLS EFGMMFPVLG PRSECSGASS PECEVERGDR AEGAENKTSD KANNNRG
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
Protein Aliases: SH3 binding protein; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3-domain binding protein 5 (BTK-associated); SH3BP-5
Gene Aliases: SAB; SH3BP-5; SH3BP5
UniProt ID: (Human) O60239
Entrez Gene ID: (Human) 9467
Molecular Function: scaffold/adaptor protein