This antibody is predicted to react with human and rat based on sequence homology.
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
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Protein Aliases: COPII-associated small GTPase; GTP-binding protein SAR1a; masra2; SAR1; SAR1 gene homolog A; SAR1 homolog A; SAR1A; SAR1a gene homolog 1; Sara; SARA1; secretion associated, Ras related GTPase 1A
Gene Aliases: 1600019H17Rik; masra2; SAR1; SAR1A; SARA; SARA1
UniProt ID: (Human) Q9NR31