PA5-28982 targets SREBF chaperone protein in WB applications and shows reactivity with Human samples.
The PA5-28982 immunogen is recombinant fragment corresponding to a region within amino acids 977 and 1224 of Human SREBF chaperone protein.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
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Protein Aliases: SCAP; Sreb cleavage-activating protein; SREBP cleavage activating protein; SREBP cleavage-activating protein; sterol regulatory element binding protein cleavage-activating protein; Sterol regulatory element-binding protein cleavage-activating protein
Gene Aliases: 9530044G19; KIAA0199; mKIAA0199; PSEC0227; SCAP