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Invitrogen
SCAP Polyclonal Antibody
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FIGURE: 1 / 11
SCAP Antibody (PA5-28982) in IHC (P)
SREBF chaperone protein antibody [C2C3], C-term detects SREBF chaperone protein protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. SREBF chaperone protein antibody [C2C3], C-term (Product # PA5-28982) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-28982
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human SCAP. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HepG2, MCF-7.
Predicted reactivity: Mouse (91%), Rat (95%), Pig (97%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: SCAP; Sreb cleavage-activating protein; SREBP cleavage activating protein; SREBP cleavage-activating protein; sterol regulatory element binding protein cleavage-activating protein; Sterol regulatory element-binding protein cleavage-activating protein
Gene Aliases: 9530044G19; KIAA0199; mKIAA0199; PSEC0227; SCAP
UniProt ID: (Human) Q12770, (Mouse) Q6GQT6
Entrez Gene ID: (Human) 22937, (Mouse) 235623
response to hypoxia
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
regulation of fatty acid metabolic process
response to insulin
SREBP signaling pathway
regulation of fatty acid biosynthetic process
regulation of cholesterol biosynthetic process
aging
negative regulation of cholesterol biosynthetic process
positive regulation of low-density lipoprotein particle receptor biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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