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Invitrogen
SCFD1 Polyclonal Antibody
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Product Details
PA5-51966
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SCFD1. Recombinant protein control fragment (Product #RP-89027).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AALAASAVTQ VAKVFDQYLN FITLEDDMFV LCNQNKELVS YRAINRPDIT DTEMETVMDT IVDSLFCFFV TLGAVPIIRC SRGTAAEMVA VKLDKKLREN LRDARNSLFT GDTLGAGQFS FQRPL
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Sec1 family domain-containing protein 1; SLY1 homolog; Sly1p; Syntaxin-binding protein 1-like 2; vesicle transport-related protein
Gene Aliases: C14orf163; FKSG23; KIAA0917; RA410; SCFD1; SLY1; SLY1P; STXBP1L2
UniProt ID: (Human) Q8WVM8
Entrez Gene ID: (Human) 23256
cell morphogenesis
response to hypoxia
retrograde vesicle-mediated transport, Golgi to ER
post-Golgi vesicle-mediated transport
vesicle docking involved in exocytosis
phagocytosis
response to toxic substance
protein transport
COPII vesicle coating
regulation of protein transport
regulation of ER to Golgi vesicle-mediated transport
toxin transport
negative regulation of autophagosome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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