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Alomone Labs, LTD
SCN3A (NaV1.3) Polyclonal Antibody
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FIGURE: 1 / 3
SCN3A (NaV1.3) Antibody (ASC-004-200UL) in ICC/IF
Expression of NaV1.3 in rat DRG primary cells - Immunocytochemical staining of paraformaldehyde-fixed and permeabilized rat dorsal root ganglia (DRG) primary culture. A. DRG cells were stained using Anti-SCN3A (NaV1.3) Antibody (#ASC-004), (1:200) followed by goat Anti-rabbit-AlexaFluor-555 secondary Antibody . B. Nuclear staining of cells using the cell-permeable dye Hoechst 33342. C. Merged image of panel... View More
Product Details
ASC-004-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)HLEGNHRADGDRFP, corresponding to amino acid residues 511-524 rat NaV1.3, Intracellular, loop between domains I and II
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
200 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BIII; brain III voltage-gated sodium channel; Sodium channel protein brain III subunit alpha; Sodium channel protein type 3 subunit alpha; Sodium channel protein type III subunit alpha; sodium channel protein, brain III subunit alpha; sodium channel, voltage gated, type III alpha subunit; sodium channel, voltage-gated, type 3, alpha subunit; sodium channel, voltage-gated, type III, alpha polypeptide; unnamed protein product; Voltage-gated sodium channel subtype III; Voltage-gated sodium channel subunit alpha Nav1.3; voltage-gated sodium channel; alpha subunit domain 4, S5-S6
Gene Aliases: DEE62; EIEE62; FFEVF4; Gm1000; KIAA1356; NAC3; Nav1.3; SCIII; Scn2a; SCN3A
UniProt ID: (Human) Q9NY46, (Mouse) A2ASI5, (Rat) P08104
Entrez Gene ID: (Human) 6328, (Mouse) 20269, (Rat) 497770
action potential
ion transport
sodium ion transport
ion transmembrane transport
sodium ion transmembrane transport
behavioral response to pain
transmembrane transport
cardiac muscle cell action potential involved in contraction
membrane depolarization during action potential
neuronal action potential
sensory perception of pain
regulation of ion transmembrane transport
response to pyrethroid
cellular response to antibiotic
nervous system development
response to wounding
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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