Immunogen sequence: KDHNCHNLPE GVADLTQIDV NVQDHFWDGK GCEMICYCNF SELLCCPKDV FFGPKISFVI PCNNQ
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 86%.
Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus.
Protein Aliases: scrapie responsive gene 1; scrapie responsive protein 1; Scrapie-responsive gene 1 protein; Scrapie-responsive protein 1; ScRG-1
Gene Aliases: SCRG-1; SCRG1; UNQ390/PRO725
UniProt ID: (Human) O75711
Entrez Gene ID: (Human) 11341