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Proteintech
SCYL2 Polyclonal Antibody
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Product Details
12325-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SCYL2 Fusion Protein Ag2988 (157-505 aa encoded by BC012387)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NNLNLNQFN SFISVIKEML NRLESEHKTK LEQLHIMQEQ QKSLDIGNQM NVSEEMKVIN IGNQQIDKVF NNIGADLLTG SESENKEDGL QNKHKRASLT LEEKQKLAKE QEQAQKLKSQ QPLKPQVHTP VATVKQTKDL TDTLMDNMSS LTSLSVSTPK SSASSTFTSV PSMGIGMMFS TPTDNTKRNL TNGLNANMGF QTSGFNMPVN TNQNFYSSPS TVGVTKMTLG TPPTLPNFNA LSVPPAGAKQ TQQRPTDMSA LNNLFGPQKP KVSMNQLSQQ KPNQWLNQFV PPQGSPTMGS SVMGTQMNVI GQSAFGMQGN PFFNPQNFAQ PPTTMTNSSS ASNDLKDLFG (157-505 aa encoded by BC012387)
Target Information
SCYL2 is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. SCYL2 is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. SCYL2 may also regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Coated vesicle-associated kinase of 104 kDa; SCY1-like 2; SCY1-like protein 2; SCY1-like, kinase-like 2; unnamed protein product
Gene Aliases: AMC4; AMCNACC; AU015688; AW536445; BC030932; CVAK104; D10Ertd802e; KIAA1360; RGD1305665; SCYL2
UniProt ID: (Human) Q6P3W7, (Mouse) Q8CFE4
Entrez Gene ID: (Human) 55681, (Rat) 314717, (Mouse) 213326
brain development
endosome to lysosome transport
pyramidal neuron development
receptor internalization
clathrin-mediated endocytosis
negative regulation of canonical Wnt signaling pathway
positive regulation of receptor internalization
protein phosphorylation
receptor internalization involved in canonical Wnt signaling pathway
positive regulation of clathrin-mediated endocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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