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Proteintech
SDHC Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
14575-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SDHC Fusion Protein Ag5775 (1-169 aa encoded by BC033626)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAALLLRHV GRHCLRAHFS PQLCIRNAVP LGTTAKEEME RFWNKNIGSN RPLSPHITIY SWSLPMAMSI CHRGTGIALS AGVSLFGMSA LLLPGNFESY LELVKSLCLG PALIHTAKFA LVFPLMYHTW NGIRHLMWDL GKGLKIPQLY QSGVVVLVLT VLSSMGLAAM (1-169 aa encoded by BC033626)
Target Information
This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cytochrome B large subunit of complex II; integral membrane protein CII-3; integral membrane protein CII-3b; large subunit of cytochrome b; malate dehydrogenase [quinone] cytochrome b560 subunit; QPs-1; QPS1; SDHC; succinate dehydrgenase cytochrome b; succinate dehydrogenase 3, integral membrane subunit; succinate dehydrogenase complex subunit C integral membrane protein 15kDa; succinate dehydrogenase complex, subunit C, integral membrane protein; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD; succinate-ubiquinone oxidoreductase cytochrome B large subunit; unnamed protein product
Gene Aliases: 0610010E03Rik; CYB560; CYBL; PGL3; PPGL3; QPS1; SDH3
UniProt ID: (Human) Q99643, (Mouse) Q9CZB0
Entrez Gene ID: (Human) 6391, (Mouse) 66052, (Rat) 289217
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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