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Immunogen sequence: AASQLILPDS MKVLPVYMNC LLKNCVLLSR PEISTDERAY QRQLVMTMGV ADSQLFFYPQ LLPIHTLDVK STMLPAAVRC SESRLSEEGI FLLANGLHMF LWLGVSSPPE LIQGIFNVPS FAHINTDMTL LPEVGNPYSQ QLRMIMGIIQ QKRPYSMKLT IVKQREQPEM V; Positive Samples: LO2, BxPC-3, A-375, DU145, Mouse liver; Cellular Location: Cytoplasm, Endoplasmic reticulum membrane, Golgi apparatus membrane, perinuclear region
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration.
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Protein Aliases: Protein transport protein Sec24D; SEC24 family, member D; SEC24 related gene family, member D; SEC24-related protein D
Gene Aliases: 2310020L09Rik; CLCRP2; Gm1349; KIAA0755; SEC24D
UniProt ID: (Human) O94855
Entrez Gene ID: (Human) 9871, (Mouse) 69608, (Rat) 310843
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