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Product Details
PA5-103169
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SEMA4C(Accession Q9C0C4), corresponding to amino acid residues P733-N783.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2852539
Product Specific Information
Antibody detects endogenous levels of total SEMA4C.
Target Information
SEMA4C (semaphorin-4C), also known as SEMAF, is an 833 amino acid single-pass type I membrane protein that contains one sema domain, one PSI domain and one Ig-like C2-type domain. Expressed in a variety of tissues, including lung, kidney and brain, SEMA4C interacts with GIPC and NCDN and is thought to play a role in the formation of neural networks during development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ20369; M-Sema F; MGC126382; MGC126383; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C; Semaphorin-4C
Gene Aliases: KIAA1739; M-SEMA-F; SEMA4C; SEMACL1; SEMAF; SEMAI; UNQ5855/PRO34487
UniProt ID: (Human) Q9C0C4
Entrez Gene ID: (Human) 54910
neural crest cell migration
neural tube closure
cell migration in hindbrain
cerebellum development
positive regulation of cell migration
positive regulation of stress-activated MAPK cascade
muscle cell differentiation
negative regulation of axon extension involved in axon guidance
negative chemotaxis
semaphorin-plexin signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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