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Invitrogen
SERPINA3 Polyclonal Antibody
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Product Details
PA1-4150
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
N-terminus of human ACT.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-4150 detects the ACT protein in human samples.
PA1-4150 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~33 kDa protein representing the ACT protein in testis extract.
The PA1- 4150 immunogen is the N-terminus of the human ACT protein.
Target Information
SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACT; alpha-1 antichymotrypsin N; ACT-N; alpha-1 antichymotrypsin T; ACT-T; Alpha-1-antichymotrypsin; alpha-1-antichymotrypsin precursor; Cell growth-inhibiting gene 24/25 protein; Growth inhibiting protein 24; Growth inhibiting protein 25; growth-inhibiting protein 24; growth-inhibiting protein 25; MGC88254; Serine (or cysteine) proteinase inhibitor clade A member 3; serine (or cysteine) proteinase inhibitor, clade A, member 3; Serpin A3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; unnamed protein product
Gene Aliases: AACT; ACT; GIG24; GIG25; SERPINA3
UniProt ID: (Human) P01011
Entrez Gene ID: (Human) 12
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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