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Proteintech
SERPINB3 Polyclonal Antibody
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Product Details
26558-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SERPINB3 Fusion Protein Ag24846 (275-390 aa encoded by BC005224)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRETRVDLH LPRFKVEESY DLKDTLRTMG MVDIFNGDAD LSGMTGSRGL VLSGVLHKAF VEVTEEGAEA AAATAVVGFG SSPTSTNEEF HCNHPFLFFI RQNKTNSILF YGRFSSP (275-390 aa encoded by BC005224 )
Target Information
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protein T4-A; SCCA-1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; Serpin B3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; spb3; Squamous cell carcinoma antigen 1
Gene Aliases: HsT1196; SCC; SCCA; SCCA-1; SCCA-PD; SCCA1; SERPINB3; SSCA1; T4-A
UniProt ID: (Human) P29508
Entrez Gene ID: (Human) 6317
positive regulation of cell proliferation
negative regulation of peptidase activity
positive regulation of epithelial to mesenchymal transition
positive regulation of endopeptidase activity
negative regulation of endopeptidase activity
positive regulation of cell migration
autocrine signaling
paracrine signaling
negative regulation of catalytic activity
negative regulation of JUN kinase activity
negative regulation of proteolysis
viral entry into host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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