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| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
1:1,000-1:2,500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human SERPINB4 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2647149 |
Immunogen sequence: QEYLDAIKKF YQTSVESTDF ANAPEESRKK I
Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 61%.
SERPINB4 is also called squamous cell carcinoma antigen 2 (SCCA-2) or leupin. It directly inhibits human granzyme proteolytic activity and that overexpression of SERPINB4 in HeLa cells inhibits recombinant granzyme-induced as well as NK cell-mediated cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Leupin; Leupin SERPINB4; Peptidase inhibitor 11; PI-11; protease inhibitor (leucine-serpin); SCCA-2; SCCA2/SCCA1 fusion protein; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; Serpin B4; serpin peptidase inhibitor, clade B (ovalbumin), member 4; squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
Gene Aliases: LEUPIN; PI11; SCCA-2; SCCA1; SCCA2; SERPINB4
UniProt ID: (Human) P48594
Entrez Gene ID: (Human) 6318
Molecular Function:
protease inhibitor
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