|ChIP assay (ChIP)||Assay-Dependent|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 421 and 700 of Human SETDB1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29101 targets SETDB1 in WB applications and shows reactivity with Human samples.
The PA5-29101 immunogen is recombinant fragment corresponding to a region within amino acids 421 and 700 of Human SETDB1.
This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ERG-associated protein with a SET domain; ERG-associated protein with a SET domain, ESET; ERG-associated protein with SET domain; ESET; H3-K9-HMTase 4; H3-K9-HMTase4; H3lysine-9 specific 4; Histone H3-K9 methyltransferase 4; histone-lysine N-methyltransferase; Histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase, H3lysine-9 specific 4; KG1T; KMT1E; lysine N-methyltrans; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SET domain, bifurcated 1; tudor domain containing 21
Gene Aliases: ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; SETDB1; TDRD21
UniProt ID: (Human) Q15047
Entrez Gene ID: (Human) 9869
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