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Abnova
SFN Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 2
SFN Antibody (H00002810-D01P) in WB
Western Blot analysis of SFN expression in transfected 293T cell line (H00002810-T01) by SFN MaxPab polyclonal antibody.
Lane 1: SFN transfected lysate(27.80 KDa).
Lane 2: Non-transfected lysate.
Lane 1: SFN transfected lysate(27.80 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00002810-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SFN (NP_006133.1, 1 a.a. approximately 248 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG EAPQEPQS
Target Information
This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14-3-3 protein sigma; 14-3-3sigma; Epithelial cell marker protein 1; HGNC:10773; SFN; Stratifin
Gene Aliases: HME1; SFN; YWHAS
UniProt ID: (Human) P31947
Entrez Gene ID: (Human) 2810
negative regulation of transcription from RNA polymerase II promoter
release of cytochrome c from mitochondria
keratinocyte development
negative regulation of protein kinase activity
protein export from nucleus
signal transduction
protein localization
intrinsic apoptotic signaling pathway in response to DNA damage
regulation of epidermal cell division
negative regulation of keratinocyte proliferation
regulation of cell-cell adhesion
keratinocyte differentiation
positive regulation of cell growth
keratinization
regulation of protein localization
defense response to bacterium
skin development
keratinocyte proliferation
positive regulation of epidermal cell differentiation
positive regulation of cell adhesion
negative regulation of innate immune response
positive regulation of protein export from nucleus
cytolysis in other organism
regulation of cell cycle
establishment of skin barrier
stem cell proliferation
cAMP/PKA signal transduction
non-canonical inflammasome complex assembly
negative regulation of protein localization to plasma membrane
positive regulation of cellular protein localization
negative regulation of stem cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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