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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MSGCRVFIG RLNPAAREKD VERFFKGYGR IRDIDLKRGF GFVEFEDPRD ADDAVYELDG KELCSERVTI EHARARSRGG RGRGRYSDRF SSRRPRNDRR NAPPVRTENR LIVENLSSRV SWQDLKDFMR QAGEVTFADA HRPKLNEGVV EFASYGDLKN AIEKLSGKEI NGRKIKLIEG SKRHSRSRSR SRSRTRSSSR SRSRSRSRSR KSYSRSRSRS RSRSRSKSRS VSRSPVPEKS QKRGSSSRSK SPASVDRQRS RSRSRSRSVD SGN (1-272 aa encoded by BC018823)
SR proteins are a highly conserved family of arginine/serine-rich, spliceosome-associated phosphoproteins essential for metazoan pre-mRNA splicing. SR proteins act early in splicing by promoting splice site recognition and spliceosome assembly. SR proteins also play a regulatory role because they can determine alternative splice site usage in vivo and in vitro. SR proteins appear to be recruited from nuclear 'speckles', in which they are concentrated to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: delayed-early protein HRS; insulin-induced growth response protein CL-4; pre-mRNA-splicing factor SRP40; putative; SFRS5; splicing factor, arginine/serine-rich 5; splicing factor, arginine/serine-rich 5 (SRp40, HRS); SR splicing factor 5; unnamed protein product
Gene Aliases: HRS; SFRS5; SRP40
UniProt ID: (Human) Q13243, (Mouse) O35326, (Rat) Q09167
Entrez Gene ID: (Human) 6430, (Mouse) 20384, (Rat) 29667
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