Sodium-dependent glucose transporter. Has a Na+ to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.
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Protein Aliases: low affinity sodium-dependent glucose cotransporter; Low affinity sodium-glucose cotransporter; Na(+)/glucose cotransporter 2; SGLT-2; Sodium/glucose cotransporter 2; solute carrier family 5 (sodium/glucose cotransporter), member 2; solute carrier family 5 (sodium/glucose transporter), member 2; Solute carrier family 5 member 2
Gene Aliases: SGLT2; SLC5A2
Molecular Function: secondary carrier transporter