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Invitrogen
SH2B1 Polyclonal Antibody
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Product Details
PA5-149271
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human SH2B1, Pro317-Leu467
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp547G1110; FceRI gamma-chain-interacting protein SH2-B; FLJ30542; Pro-rich, PH and SH2 domain-containing signaling mediator; PSM; SH2 B; SH2 domain-containing protein 1B; SH2 domain-containing putative adapter SH2-B; SH2-B PH domain containing signaling mediator 1; SH2-B PH domain-containing signaling mediator 1; SH2-B signaling protein; SH2B adapter protein 1; SH2B1 protein; unnamed protein product
Gene Aliases: AI425885; C530001K22Rik; Irip; KIAA1299; mKIAA1299; PSM; SH2-B; SH2-Bb; SH2B; SH2B1; Sh2bpsm1
UniProt ID: (Human) Q9NRF2, (Rat) Q62985, (Mouse) Q91ZM2
Entrez Gene ID: (Human) 25970, (Rat) 89817, (Mouse) 20399
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
lamellipodium assembly
intracellular signal transduction
positive regulation of mitotic nuclear division
cell motility
positive regulation of SMAD protein import into nucleus
regulation of DNA biosynthetic process
movement of cell or subcellular component
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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