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Proteintech
SH3GL2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
12435-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SH3GL2 Fusion Protein Ag3114 (1-279 aa encoded by BC032825)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.28 mg/mL
Amount
42 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSVAGLKKQ FHKATQKVSE KVGGAEGTKL DDDFKEMERK VDVTSRAVME IMTKTIEYLQ PNPASRAKLS MINTMSKIRG QEKGPGYPQA EALLAEAMLK FGRELGDDCN FGPALGEVGE AMRELSEVKD SLDIEVKQNF IDPLQNLHDK DLREIQHHLK KLEGRRLDFD YKKERQGKIP DEELRQALEK FDESKEIAES SMFNLLEMDI EQVSQLSALV QAQLEYHKQA VQILQQVTVR LEERIRQASS QPRREYQPKP RMSLEFPTGD STQPNGGLSH (1-279 aa encoded by BC032825)
Target Information
Enables identical protein binding activity. Involved in negative regulation of blood-brain barrier permeability; negative regulation of gene expression; and negative regulation of protein phosphorylation. Located in perinuclear region of cytoplasm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bA335L15.1; bA335L15.1 (SH3-domain GRB2-like 2); contains SH3 domain; endophilin; Endophilin A1 BAR domain; endophilin I; endophilin-1; FLJ20276; FLJ25015; SH3 domain protein 2A; SH3 domain-containing GRB2-like 2; SH3 domain-containing GRB2-like protein 2; SH3-domain GRB2-like 2; SH3GL2; SH3p4; similar to endophilin 1; unnamed protein product
Gene Aliases: 9530001L19Rik; B930049H17Rik; CNSA2; EEN-B1; EEN1; SH3D2A; SH3P4; SH3PA
UniProt ID: (Human) Q99962, (Rat) O35179, (Mouse) Q62420
Entrez Gene ID: (Human) 6456, (Rat) 116743, (Mouse) 20404
signal transduction
central nervous system development
negative regulation of gene expression
neuron projection development
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of MAPK cascade
synaptic vesicle endocytosis
dendrite extension
membrane tubulation
postsynaptic actin cytoskeleton organization
negative regulation of blood-brain barrier permeability
cellular response to brain-derived neurotrophic factor stimulus
regulation of receptor internalization
regulation of endocytosis
lipid tube assembly
membrane bending
vesicle scission
positive regulation of membrane tubulation
regulation of clathrin-mediated endocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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