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Invitrogen
SH3GL2 Polyclonal Antibody
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FIGURE: 1 / 2
SH3GL2 Antibody (PA5-101888) in ICC/IF
Immunocytochemistry analysis of SH3GL2 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SH3GL2 polyclonal antibody (Product # PA5-101888) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-101888
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SH3GL2(Accession Q99962), corresponding to amino acid residues M51-G101.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SH3GL2.
Target Information
Enables identical protein binding activity. Involved in negative regulation of blood-brain barrier permeability; negative regulation of gene expression; and negative regulation of protein phosphorylation. Located in perinuclear region of cytoplasm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bA335L15.1; bA335L15.1 (SH3-domain GRB2-like 2); EEN-B1; endophilin; endophilin A1; Endophilin A1 BAR domain; endophilin I; Endophilin-1; Endophilin-A1; FLJ20276; FLJ25015; SH3 domain containing GRB2 like 2; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2; SH3-domain GRB2-like 2; SH3p4
Gene Aliases: 9530001L19Rik; AI120490; AW555077; B930049H17Rik; CNSA2; EEN-B1; Een1; SH3D2A; SH3GL2; SH3P4; SH3PA
UniProt ID: (Human) Q99962, (Mouse) Q62420, (Rat) O35179
Entrez Gene ID: (Human) 6456, (Mouse) 20404, (Rat) 116743
regulation of receptor internalization
endocytosis
synaptic vesicle endocytosis
microtubule-based movement
signal transduction
central nervous system development
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of epidermal growth factor receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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