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Invitrogen
SH3RF2 Polyclonal Antibody
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Product Details
PA5-21013
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 17 amino acid peptide near the carboxy terminus of human SH3RF2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is NIH-3T3 cell lysate.
PA5-21013 can be used with blocking peptide PEP-1127.
Target Information
The SH3RF2 gene encodes a protein that has been shown to possess protein phosphatase 1 binding activity and ubiquitin protein ligase activity. This protein is involved in several cellular processes, including the positive regulation of the JNK cascade, protein autoubiquitination, and regulation of cellular protein metabolic processes. The protein is located in the nucleoplasm and mutations in the SH3RF2 gene have been associated with Ureter Transitional Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase SH3RF2; Heart protein phosphatase 1-binding protein; HEPP1; phosphatase 1 binding protein; POSH-eliminating RING protein; Protein phosphatase 1 regulatory subunit 39; protein phosphatase 1, regulatory subunit 39; putative E3 ubiquitin-protein ligase SH3RF2; RING finger protein 158; RING-type E3 ubiquitin transferase SH3RF2; SH3 domain-containing RING finger protein 2
Gene Aliases: 2310046K19; 9130023G24Rik; AI452083; HEPP1; Posh2; POSH3; POSHER; PPP1R39; RNF158; SH3RF2
UniProt ID: (Human) Q8TEC5, (Rat) Q498M5, (Mouse) Q8C1E3
Entrez Gene ID: (Human) 153769, (Rat) 307472, (Mouse) 269016
protein phosphatase inhibitor activity
protein binding
protein phosphatase 1 binding
zinc ion binding
ligase activity
phosphatase binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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