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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (SRQTATALPTGTSKC) corresponding to the N-terminus amino acids of SIAH1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This product is expected to recognize both reported isoforms (NP_003022.3; NP_001006611.1).
This antibody is predicted to react with bovine and canine based on sequence homology.
This gene encodes a protein that is a member of the seven in absentia homolog family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase SIAH1A; FLJ08065; hSIAH1; HUMSIAH; mSiah-1a; seven in absentia 1A; seven in absentia homolog 1; seven in absentia homolog 1 (Drosophila); seven in absentia homolog 1a; Siah-1; siah-1a; SIAH1; sonic hedgehog homolog
AA982064; AI853500; HUMSIAH; SIAH; SIAH1; SIAH1A; Sinh1a