Product References
Resveratrol Improves the Energy Sensing and Glycolipid Metabolism of Blunt Snout Bream Megalobrama amblycephala Fed High-Carbohydrate Diets by Activating the AMPK-SIRT1-PGC-1α Network.
Frontiers in physiology
Shi HJ,Xu C,Liu MY,Wang BK,Liu WB,Chen DH,Zhang L,Xu CY,Li XF
Thu Oct 01 00:00:00 EDT 2020
Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats.
Evidence-based complementary and alternative medicine : eCAM
Luo D,Liu L,Liang FX,Yu ZM,Chen R
Wed Sep 30 00:00:00 EDT 2020
Modified Si-Ni-San Decoction Ameliorates Central Fatigue by Improving Mitochondrial Biogenesis in the Rat Hippocampus.
Evidence-based complementary and alternative medicine : eCAM
Han C,Li F,Liu Y,Ma J,Yu X,Wu X,Zhang W,Li D,Chen D,Dai N,Lin B,Wu F,Mao M
Tue Sep 29 00:00:00 EDT 2020
Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer.
Journal of cellular physiology
Pan JH,Zhou H,Zhu SB,Huang JL,Zhao XX,Ding H,Qin L,Pan YL
Mon Apr 01 00:00:00 EDT 2019
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
Autophagy
Hu X,Lu Z,Yu S,Reilly J,Liu F,Jia D,Qin Y,Han S,Liu X,Qu Z,Lv Y,Li J,Huang Y,Jiang T,Jia H,Wang Q,Liu J,Shu X,Tang Z,Liu M
Fri Mar 01 00:00:00 EST 2019
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
Autophagy
Hu X,Lu Z,Yu S,Reilly J,Liu F,Jia D,Qin Y,Han S,Liu X,Qu Z,Lv Y,Li J,Huang Y,Jiang T,Jia H,Wang Q,Liu J,Shu X,Tang Z,Liu M
Fri Mar 01 00:00:00 EST 2019
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Brain, behavior, and immunity
Xu B,Zang SC,Li SZ,Guo JR,Wang JF,Wang D,Zhang LP,Yang HM,Lian S
Fri Feb 01 00:00:00 EST 2019
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway.
International journal of biological sciences
Yu C,Jiao Y,Xue J,Zhang Q,Yang H,Xing L,Chen G,Wu J,Zhang S,Zhu W,Cao J
Mon Jul 30 00:00:00 EDT 2018
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Redox biology
Li D,Wang X,Huang Q,Li S,Zhou Y,Li Z
Tue May 01 00:00:00 EDT 2018
Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications.
Biochemical pharmacology
Wang Z,Yuan S,Li Y,Zhang Z,Xiao W,Tang D,Ye K,Liu Z,Wang C,Zheng Y,Nie H,Chen H
Sun Apr 01 00:00:00 EDT 2018
Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.
Nucleic acids research
Chen R,Liu Y,Zhuang H,Yang B,Hei K,Xiao M,Hou C,Gao H,Zhang X,Jia C,Li L,Li Y,Zhang N
Fri Sep 29 00:00:00 EDT 2017
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
PloS one
Ran G,Ying L,Li L,Yan Q,Yi W,Ying C,Wu H,Ye X
Fri Sep 22 00:00:00 EDT 2017
Salidroside ameliorates sepsis-induced acute lung injury and mortality via downregulating NF-κB and HMGB1 pathways through the upregulation of SIRT1.
Scientific reports
Lan KC,Chao SC,Wu HY,Chiang CL,Wang CC,Liu SH,Weng TI
Wed Sep 20 00:00:00 EDT 2017
The Effects of Resveratrol on Inflammation and Oxidative Stress in a Rat Model of Chronic Obstructive Pulmonary Disease.
Molecules (Basel, Switzerland)
Wang XL,Li T,Li JH,Miao SY,Xiao XZ
Tue Sep 12 00:00:00 EDT 2017
The Effects of Resveratrol on Inflammation and Oxidative Stress in a Rat Model of Chronic Obstructive Pulmonary Disease.
Molecules (Basel, Switzerland)
Wang XL,Li T,Li JH,Miao SY,Xiao XZ
Tue Sep 12 00:00:00 EDT 2017
Regulation of autophagy by AMP-activated protein kinase/sirtuin 1 pathway reduces spinal cord neurons damage.
Iranian journal of basic medical sciences
Yan P,Bai L,Lu W,Gao Y,Bi Y,Lv G
Fri Sep 01 00:00:00 EDT 2017
Regulation of autophagy by AMP-activated protein kinase/sirtuin 1 pathway reduces spinal cord neurons damage.
Iranian journal of basic medical sciences
Yan P,Bai L,Lu W,Gao Y,Bi Y,Lv G
Fri Sep 01 00:00:00 EDT 2017
Short- and Long-Term Hindlimb Immobilization and Reloading: Profile of Epigenetic Events in Gastrocnemius.
Journal of cellular physiology
Chacon-Cabrera A,Gea J,Barreiro E
Thu Jun 01 00:00:00 EDT 2017
TRPC5 channel modulates endothelial cells senescence.
European journal of pharmacology
Li Z,Guo G,Wang H,Si X,Zhou G,Xiong Y,Li S,Dai R,Yang C
Fri May 05 00:00:00 EDT 2017
Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: evidence for an anti-inflammatory cascade mediated by the miR-221/222/AMPK/p38/NF-κB pathway.
Scientific reports
Liu CW,Sung HC,Lin SR,Wu CW,Lee CW,Lee IT,Yang YF,Yu IS,Lin SW,Chiang MH,Liang CJ,Chen YL
Fri Mar 24 00:00:00 EDT 2017
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
Scientific reports
Zhang C,Li C,Chen S,Li Z,Ma L,Jia X,Wang K,Bao J,Liang Y,Chen M,Li P,Su H,Lee SM,Liu K,Wan JB,He C
Mon Jan 23 00:00:00 EST 2017
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Transplantation proceedings
Zhang P,Li Y,Du Y,Li G,Wang L,Zhou F
Thu Dec 01 00:00:00 EST 2016
Effects of physical exercise on myokines expression and brown adipose-like phenotype modulation in rats fed a high-fat diet.
Life sciences
Rocha-Rodrigues S,Rodríguez A,Gouveia AM,Gonçalves IO,Becerril S,Ramírez B,Beleza J,Frühbeck G,Ascensão A,Magalhães J
Tue Nov 15 00:00:00 EST 2016
Lycium barbarum polysaccharide attenuates high-fat diet-induced hepatic steatosis by up-regulating SIRT1 expression and deacetylase activity.
Scientific reports
Jia L,Li W,Li J,Li Y,Song H,Luan Y,Qi H,Ma L,Lu X,Yang Y
Tue Nov 08 00:00:00 EST 2016
Capsaicin reactivates hMOF in gastric cancer cells and induces cell growth inhibition.
Cancer biology & therapy
Wang F,Zhao J,Liu D,Zhao T,Lu Z,Zhu L,Cao L,Yang J,Jin J,Cai Y
Tue Nov 01 00:00:00 EDT 2016
The Polyphenol Oleuropein Aglycone Modulates the PARP1-SIRT1 Interplay: An In Vitro and In Vivo Study.
Journal of Alzheimer's disease : JAD
Luccarini I,Pantano D,Nardiello P,Cavone L,Lapucci A,Miceli C,Nediani C,Berti A,Stefani M,Casamenti F
Tue Sep 06 00:00:00 EDT 2016
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Molecules (Basel, Switzerland)
Zhao L,Xu L,Tao X,Han X,Yin L,Qi Y,Peng J
Thu Jul 21 00:00:00 EDT 2016
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Nutrients
Tao X,Sun X,Xu L,Yin L,Han X,Qi Y,Xu Y,Zhao Y,Wang C,Peng J
Fri Jul 08 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Environmental toxicology and pharmacology
Zhang W,Yin L,Tao X,Xu L,Zheng L,Han X,Xu Y,Wang C,Peng J
Fri Jul 01 00:00:00 EDT 2016
RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway.
PloS one
Gu A,Jie Y,Sun L,Zhao S,E M,You Q
Mon May 23 00:00:00 EDT 2016
Sirtuin 1 Promotes Hyperoxia-Induced Lung Epithelial Cell Death Independent of NF-E2-Related Factor 2 Activation.
American journal of respiratory cell and molecular biology
Potteti HR,Rajasekaran S,Rajamohan SB,Tamatam CR,Reddy NM,Reddy SP
Sun May 01 00:00:00 EDT 2016
Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling.
Scientific reports
Liu F,Zhang W,Yang F,Feng T,Zhou M,Yu Y,Yu X,Zhao W,Yi F,Tang W,Lu Y
Tue Feb 16 00:00:00 EST 2016
Sirt1 is involved in decreased bone formation in aged apolipoprotein E-deficient mice.
Acta pharmacologica Sinica
Hong W,Xu XY,Qiu ZH,Gao JJ,Wei ZY,Zhen L,Zhang XL,Ye ZB
Tue Dec 01 00:00:00 EST 2015
Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum.
The journal of sexual medicine
Freitas M,Rodrigues AR,Tomada N,Fonseca J,Magalhães A,Gouveia AM,Neves D
Sun Nov 01 00:00:00 EDT 2015
Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum.
The journal of sexual medicine
Freitas M,Rodrigues AR,Tomada N,Fonseca J,Magalhães A,Gouveia AM,Neves D
Sun Nov 01 00:00:00 EDT 2015
Curcumin treatment enhances the effect of exercise on mitochondrial biogenesis in skeletal muscle by increasing cAMP levels.
Metabolism: clinical and experimental
Ray Hamidie RD,Yamada T,Ishizawa R,Saito Y,Masuda K
Thu Oct 01 00:00:00 EDT 2015
Ubiquitin-specific peptidase USP22 negatively regulates the STAT signaling pathway by deubiquitinating SIRT1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Ao N,Liu Y,Feng H,Bian X,Li Z,Gu B,Zhao X,Liu Y
Mon Sep 21 00:00:00 EDT 2015
Ubiquitin-specific peptidase USP22 negatively regulates the STAT signaling pathway by deubiquitinating SIRT1.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Ao N,Liu Y,Feng H,Bian X,Li Z,Gu B,Zhao X,Liu Y
Mon Sep 21 00:00:00 EDT 2015
Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.
Asian journal of andrology
Pereira CD,Severo M,Rafael L,Martins MJ,Neves D
Fri Aug 21 00:00:00 EDT 2015
Effects of natural mineral-rich water consumption on the expression of sirtuin 1 and angiogenic factors in the erectile tissue of rats with fructose-induced metabolic syndrome.
Asian journal of andrology
Pereira CD,Severo M,Rafael L,Martins MJ,Neves D
Fri Aug 21 00:00:00 EDT 2015
Quadriceps muscle weakness and atrophy are associated with a differential epigenetic profile in advanced COPD.
Clinical science (London, England : 1979)
Puig-Vilanova E,Martínez-Llorens J,Ausin P,Roca J,Gea J,Barreiro E
Mon Jun 01 00:00:00 EDT 2015
Do epigenetic events take place in the vastus lateralis of patients with mild chronic obstructive pulmonary disease?
PloS one
Puig-Vilanova E,Ausin P,Martinez-Llorens J,Gea J,Barreiro E
Wed Mar 04 00:00:00 EST 2015
Natural mineral-rich water ingestion improves hepatic and fat glucocorticoid-signaling and increases sirtuin 1 in an animal model of metabolic syndrome.
Hormone molecular biology and clinical investigation
Pereira CD,Severo M,Neves D,Ascensão A,Magalhães J,Guimarães JT,Monteiro R,Martins MJ
Sun Feb 01 00:00:00 EST 2015
Expression of hMOF in different ovarian tissues and its effects on ovarian cancer prognosis.
Oncology reports
Cai M,Hu Z,Liu J,Gao J,Tan M,Zhang D,Zhu L,Liu S,Hou R,Lin B
Sun Feb 01 00:00:00 EST 2015
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
PloS one
Xu Q,Xia P,Li X,Wang W,Liu Z,Gao X
Mon Sep 29 00:00:00 EDT 2014
Tetramethylpyrazine ameliorates high glucose-induced endothelial dysfunction by increasing mitochondrial biogenesis.
PloS one
Xu Q,Xia P,Li X,Wang W,Liu Z,Gao X
Mon Sep 29 00:00:00 EDT 2014
The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway.
Cell death & disease
Xu R,Hu Q,Ma Q,Liu C,Wang G
Thu Aug 14 00:00:00 EDT 2014
The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway.
Cell death & disease
Xu R,Hu Q,Ma Q,Liu C,Wang G
Thu Aug 14 00:00:00 EDT 2014
MiR-138 induces renal carcinoma cell senescence by targeting EZH2 and is downregulated in human clear cell renal cell carcinoma.
Oncology research
Liang J,Zhang Y,Jiang G,Liu Z,Xiang W,Chen X,Chen Z,Zhao J
Tue Aug 05 00:00:00 EDT 2014
Exogenous NAD(+) supplementation protects H9c2 cardiac myoblasts against hypoxia/reoxygenation injury via Sirt1-p53 pathway.
Fundamental & clinical pharmacology
Liu L,Wang P,Liu X,He D,Liang C,Yu Y
Tue Apr 01 00:00:00 EDT 2014
Long-term high-fat consumption leads to downregulation of Akt phosphorylation of eNOS at Ser1177 and upregulation of Sirtuin-1 expression in rat cavernous tissue.
Age (Dordrecht, Netherlands)
Tomada I,Negrão R,Almeida H,Neves D
Tue Apr 01 00:00:00 EDT 2014
Long-term high-fat consumption leads to downregulation of Akt phosphorylation of eNOS at Ser1177 and upregulation of Sirtuin-1 expression in rat cavernous tissue.
Age (Dordrecht, Netherlands)
Tomada I,Negrão R,Almeida H,Neves D
Tue Apr 01 00:00:00 EDT 2014
Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis.
PloS one
Endo H,Niioka M,Kobayashi N,Tanaka M,Watanabe T
Mon Dec 23 00:00:00 EST 2013