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Huabio
SIX2 Polyclonal Antibody
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Product Details
HA500463
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within mouse six2a aa 100-150/291.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 0.2% BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: sine oculis homeobox homolog 2; sine oculis-related homeobox 2 homolog; SIX2; unnamed protein product
UniProt ID: (Human) Q9NPC8, (Mouse) Q62232
Entrez Gene ID: (Human) 10736, (Mouse) 20472, (Rat) 366542
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
macromolecular complex binding
sequence-specific double-stranded DNA binding
transcription factor binding
metanephros development
cell fate specification
kidney development
chondrocyte differentiation
mesenchymal to epithelial transition involved in metanephros morphogenesis
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein import into nucleus
mesodermal cell fate specification
cell proliferation
anterior/posterior axis specification
cell migration
regulation of ossification
regulation of chondrocyte differentiation
middle ear morphogenesis
negative regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic cranial skeleton morphogenesis
embryonic skeletal system morphogenesis
mesenchymal cell differentiation
nephron development
nephron morphogenesis
mesenchymal stem cell maintenance involved in nephron morphogenesis
kidney mesenchyme development
nephron epithelium morphogenesis
condensed mesenchymal cell proliferation
mesenchymal cell differentiation involved in kidney development
regulation of branching involved in ureteric bud morphogenesis
mesenchymal stem cell proliferation
positive regulation of chondrocyte proliferation
anatomical structure morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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