Immunogen sequence: LVFAKYQHLP YIQILSTKST PTGLFGYWGN KGGVNICLKL YGYYVSIINC HLPPHISNNY QRLEHFDRIL EMQNCEGRDI PNILDHDLII WFGDMNFRIE DFGLHFVRES IKNRCYGGLW EKDQLSI
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.
This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: Inositol polyphosphate 5-phosphatase K; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; Phosphatidylinositol-4,5-bisphosphate 5-phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase
Gene Aliases: INPP5K; PPS; SKIP
UniProt ID: (Human) Q9BT40
Entrez Gene ID: (Human) 51763