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Proteintech
SLAIN2 Polyclonal Antibody
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Product Details
13908-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLAIN2 Fusion Protein Ag4888 (231-581 aa encoded by BC040993)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PGNSGNLKS SDRNPPLSPQ SSIDSELSAS ELDEDSIGSN YKLNDVTDVQ ILARMQEESL RQEYAATTSR RSSGSSCNST RRGTFSDQEL DAQSLDDEDD NMHHAVYPAV NRFSPSPRNS PRPSPKQSPR NSPRSRSPAR GIEYSRVSPQ PMISRLQQPR LSLQGHPTDL QTSNVKNEEK LRRSLPNLSR TSNTQVDSVK SSRSDSNFQV PNGGIPRMQP QASAIPSPGK FRSPAAPSPL ALRQPVKAFS NHGSGSPGSQ EITQLTQTTS SPGPPMVQST VSANPPSNIN SATLTRPAGT TAMRSGLPRP SAPSAGGIPV PRSKLAQPVR RSLPAPKTYG SMKDDSWKDG CY (231-581 aa encoded by BC040993)
Target Information
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ21611; SLAIN motif-containing protein 2; unnamed protein product
Gene Aliases: 5033405K12Rik; 8030444K12Rik; AI596370; KIAA1458; RGD1311593; SLAIN2
UniProt ID: (Human) Q9P270, (Mouse) Q8CI08
Entrez Gene ID: (Human) 57606, (Rat) 305310, (Mouse) 75991
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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