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Invitrogen
SLAMF8 Polyclonal Antibody
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FIGURE: 1 / 2
SLAMF8 Antibody (PA5-47220) in WB
Western blot analysis of SLAMF8 in HEK293T human embryonic kidney cell line either mock transfected, transfected with EGFP, or transfected with human BLAME. Samples were incubated in SLAMF8 polyclonal antibody (Product # PA5-47220) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Goat IgG secondary antibody. A specific band was detected for BLAME/SLAMF8 at approximately 32 kDa (as indicated). This experiment was conducted under reducing conditions.
Product Details
PA5-47220
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human BLAME/SLAMF8 Ala23-Asp233
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human NTB-A/SLAMF6 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B lymphocyte activator macrophage expressed; B-lymphocyte activator macrophage expressed; BCM-like membrane protein; CD353; FLJ20442; MGC129578; SLAM family member 8; unnamed protein product
Gene Aliases: BLAME; CD353; SBBI42; SLAMF8
UniProt ID: (Human) Q9P0V8
Entrez Gene ID: (Human) 56833
leukocyte chemotaxis involved in inflammatory response
B-1 B cell lineage commitment
immune response
negative regulation of macrophage chemotaxis
defense response to bacterium
regulation of B cell differentiation
negative regulation of respiratory burst involved in inflammatory response
negative regulation of monocyte chemotaxis
phagosome acidification
negative regulation of neutrophil migration
negative regulation of dendritic cell chemotaxis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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