Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 5 publications 5 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
SLC11A2 Fusion Protein Ag14314 (1-80 aa encoded by BC002592) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.27 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
This antibody detected various forms of SLC11A2 of 45-100 kDa.
Immunogen sequence: MVLGPEQKM SDDSVSGDHG ESASLGNINP AYSNPSLSQS PGDSEEYFAT YFNEKISIPE EEYSCFSFRK LWAFTGPGFL M (1-80 aa encoded by BC002592)
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dct-1; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; microcytic anemia, viable anaemia; Natural resistance-associated macrophage protein 2; NRAMP 2; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Solute carrier family 11 member 2; Solute carrier family 11 member 2 (natural resistance-associated macrophage protein 2)
Gene Aliases: AHMIO1; DCT1; DMT1; mk; NRAMP2; OK/SW-cl.20; SLC11A2; van
UniProt ID: (Human) P49281, (Mouse) P49282, (Rat) O54902
Entrez Gene ID: (Human) 4891, (Mouse) 18174, (Rat) 25715
Molecular Function:
secondary carrier transporter
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