Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1-Oct; DKFZp313N1010; FLJ25043; FLJ37489; H oct1_cds; mOCT1; Organic cation transporter 1; rOCT1; Solute carrier family 22 member 1; solute carrier family 22, member 1; SYK
Gene Aliases: Lx1; Oct1; Orct; Orct1; Roct1; Slc22a1
Molecular Function: secondary carrier transporter