PA5-29181 targets SLC25A22 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-29181 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 323 of Human SLC25A22.
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The SLC25 gene family encodes mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane (Palmieri, 2004 [PubMed 14598172]). SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18 (MIM 609303).
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Protein Aliases: EIEE3; GC-1; GC1; Glutamate/H(+) symporter 1; Mitochondrial glutamate carrier 1; NET44; solute carrier family 25 (mitochondrial carrier: glutamate), member 22; Solute carrier family 25 member 22
Gene Aliases: 1300006L01Rik; AI060884; EIEE3; GC-1; GC1; NET44; SLC25A22
Molecular Function: RNA binding protein amino acid transporter calcium-binding protein calmodulin intracellular calcium-sensing protein mitochondrial carrier protein nucleic acid binding ribosomal protein transfer/carrier protein transporter