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Positive test controls include: HT-29, 293T, K-562, Mouse thymus. The target is usually found in the following locations: Mitochondrion inner membrane, Multi-pass membrane protein.^M
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Immunogen sequence: LGGVDKHTQF WRYFAGNLAS GGAAGATSLC FVYPLDFART RLAADVGKSG TEREFRGLGD CLVKITKSDG IRGLYQGFSV SVQGIIIYRA AYFGVYDTAK G
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.
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Protein Aliases: Adenine nucleotide translocator 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ADP,ATP carrier protein, liver; ADP/ATP translocase 3; ADP/ATP translocator of liver; ANT 2; ANT 3; Mitochondrial S-adenosylmethionine carrier protein; mitochondrial S-adenosylmethionine transporter; S-adenosylmethionine mitochondrial carrier protein; SAM carrier; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; Solute carrier family 25 member 26; Solute carrier family 25 member 6
Gene Aliases: 4930433D19Rik; 4933433F13Rik; AAC3; ANT; ANT 2; ANT 3; ANT3; ANT3Y; AW557176; CDABP0051; D6Bwg0781e; Samc; Slc25a26; SLC25A6
UniProt ID: (Human) P12236, (Mouse) Q5U680
Entrez Gene ID: (Human) 293, (Mouse) 67582
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