This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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Immunogen sequence: ESKEQHNVSP RDSAEGNDSY PSGIHLELQR ESSTDFKQFE TNDQCRPYHR ILIERQEKSD TNFKEFVIKK LQKNCQCSP
Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 51%.
The SLC26 family is comprised of sulfate/anion transporters that are well conserved in both their genomic and protein structures, yet have markedly different tissue expression patterns. Members of the SLC26 family can mediate the electroneutral exchange of Cl- for HCO3- across the plasma membrane of mammalian cells. SLC26A2 (solute carrier family 26, member 2), also known as DTD, EDM4, DTDST, MST153, D5S1708 or MSTP157, is a 739 amino acid diastrophic dysplasia sulfate transporter belonging to the SLC26A/SulP transporter family. Ubiquitously expressed, SLC26A2 may play a role in endochondral bone formation. SLC26A2 is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias and is critical for sulfation of proteoglycans and matrix organization in cartilage.
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Protein Aliases: Diastrophic dysplasia protein; solute carrier family 26 (anion exchanger), member 2; solute carrier family 26 (sulfate transporter), member 2; Solute carrier family 26 member 2; sulfate anion transporter 1; Sulfate transporter
Gene Aliases: D5S1708; DTD; DTDST; EDM4; MST153; MSTP157; SLC26A2
UniProt ID: (Human) P50443
Entrez Gene ID: (Human) 1836
Molecular Function: transporter