Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.
Protein Aliases: solute carrier family 30 (zinc transporter), member 1; Solute carrier family 30 member 1; Zinc transporter 1; ZnT-1
Gene Aliases: AI839647; C130040I11Rik; SLC30A1; ZNT1; ZRC1
Molecular Function: transporter