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Product Details
26540-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC39A14/ZIP-14 fusion protein Ag24210
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: GAPAISAASF LQDLIHRYGE GDSLTLQQLK ALLNHLDVGV GRGNVTQHVQ GHRNLSTCFS SGDLFTAHNF SEQSRIGSSE LQEFCPTILQ QLDSRACTSE NQENEENEQT EEGRPSAVE
Target Information
The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Factor for adipocyte differentiation 123; FAD-123; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; Metal cation symporter ZIP14; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; zinc transporter ZIP14; ZIP-14; Zrt- and Cig19; Zrt- and Irt-like protein 14; Zrt-, Irt-like protein 14
Gene Aliases: cig19; FAD-123; Fad123; HMNDYT2; KIAA0062; LZT-Hs4; NET34; SLC39A14; ZIP-14; ZIP14
UniProt ID: (Human) Q15043, (Mouse) Q75N73
Entrez Gene ID: (Human) 23516, (Rat) 306009, (Mouse) 213053
cellular zinc ion homeostasis
zinc II ion transmembrane transport
zinc II ion transmembrane import
ferrous iron transmembrane transport
iron ion transport
zinc II ion transport
ferrous iron transport
iron ion transmembrane transport
transport
ion transport
metal ion transport
transmembrane transport
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