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Proteintech
SLC4A1 Polyclonal Antibody
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Product Details
28131-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC4A1 Fusion Protein Ag27878 (1-200 aa encoded by BC101570)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEELQDDYE DMMEENLEQE EYEDPDIPES QMEEPAAHDT EATATDYHTT SHPGTHKVYV ELQELVMDEK NQELRWMEAA RWVQLEENLG ENGAWGRPHL SHLTFWSLLE LRRVFTKGTV LLDLQETSLA GVANQLLDRF IFEDQIRPQD REELLRALLL KHSHAGELEA LGGVKPAVLT RSGDPSQPLL PQHSSLETQL F (1-200 aa encoded by BC101570 )
Target Information
The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kDa protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AE 1; Anion exchange protein 1; anion exchanger 1; anion exchanger-1; band 3 anion exchanger; Band 3 anion transport protein; CAMP; CD233; Diego blood group; erythrocyte membrane protein band 3; erythroid anion exchange protein; Froese blood group; MEB3; MGC116750; MGC116753; MGC126619; MGC126623; solute carrier family 4 (anion exchanger), member 1 (Diego blood group); Solute carrier family 4 member 1; solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); solute carrier family 4, anion exchanger, number 1; Swann blood group; UNIMAS band 3; AE1; unnamed protein product; Waldner blood group; Wright blood group; ZNF828
Gene Aliases: AE1; BND3; CD233; CHC; DI; EMPB3; EPB3; FR; l11Jus51; RTA1A; SAO; SLC4A1; SPH4; SW; WD; WD1; WR
UniProt ID: (Human) P02730, (Mouse) P04919
Entrez Gene ID: (Human) 6521, (Mouse) 20533
inorganic anion exchanger activity
protein binding
cytoskeletal protein binding
anion transmembrane transporter activity
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
antiporter activity
hemoglobin binding
ankyrin binding
protein homodimerization activity
protein anchor
chloride:bicarbonate antiporter activity
actin binding
transporter activity
protein C-terminus binding
anion:anion antiporter activity
enzyme binding
secondary carrier transporter
ion transport
anion transport
chloride transport
cellular ion homeostasis
blood coagulation
bicarbonate transport
phospholipid scrambling
negative regulation of urine volume
pH elevation
erythrocyte development
regulation of intracellular pH
transmembrane transport
protein localization to plasma membrane
chloride transmembrane transport
negative regulation of glycolytic process through fructose-6-phosphate
transport
inorganic anion transport
anion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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